This site is for customers in Asia. Customers in China & other regions, please go to Global page.
HOME > Product search results > Code No. PM074 Anti-Phospho-p62 (SQSTM1) (Ser351) pAb

Code No.　PM074

Anti-Phospho-p62 (SQSTM1) (Ser351) pAb

Availability (in Japan)

10 or more

（In Japan at 00:05,
Apr 19, 2024 in JST）

Size

100 µL

This antibody specifically detects phospho-p62 (Ser351) in WB, IC, IHC
Data

  • Western Blotting

  • Immunoprecipitation

  • Immunocytochemistry

  • Immunohistochemistry
Clonality Polyclonal Clone Polyclonal
Isotype (Immunized Animal) Rabbit Ig (aff.)
Applications
WB
1:500  
IP
2 µL/sample  
IC
1:500  
IH
1:1,000  
Immunogen (Antigen) KLH conjugated synthetic peptide, CKEVDP(pS)TGELQSLQ (corresponding to amino acid residues 346-359 of mouse p62 (SQSTM1))
Reactivity [Gene ID]

Human[8878], Mouse[18412]
Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names Sequestosome-1, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62, EBI3-associated protein of 60 kDa, p60, EBIAP, SQSTM1, ORCA, OSIL
Related products D343-3 Anti-Phospho-p62 (SQSTM1) (Ser403) mAb
D344-3 Anti-Phospho-p62 (SQSTM1) (Ser403) mAb
PM045 Anti-p62 (SQSTM1) pAb
M162-3 Anti-p62 (SQSTM1) (Human) mAb
M162-A48 Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor™ 488
M162-A59 Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor™ 594
M162-A64 Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor™ 647
PM066 Anti-p62 C-terminal pAb
8485 Autophagy Ab Sampler Set
D343-3MS Anti-Phospho-p62 (SQSTM1) (Ser403) mAb for My select sampler set
D344-3MS Anti-Phospho-p62 (SQSTM1) (Ser403) mAb for My select sampler set
M230-3 Anti-Parkin mAb
8486 Autophagy Watch
M217-3 Anti-Phospho-p62 (SQSTM1) (Ser351) mAb
M217-3MS Anti-Phospho-p62 (SQSTM1) (Ser351) mAb for My select sampler set
M224-3 Anti-KEAP1 mAb
CY-7055 CycLex® Total p62 ELISA Kit
Citations

Western Blotting

  1. Johansson I et al. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy 11, 1636-51 (2015)(PMID:26237736)
  2. Yoshii SR et al. Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons. Dev Cell 39, 116-130 (2016)(PMID:27693508)
  3. Watanabe Y et al. HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis. Autophagy 13, 133-148 (2017)(PMID:27846364)
  4. Yanagisawa H et al. L-leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann-Pick type C disease. Sci Rep. 7, 15994 (2017)(PMID:29162837)
  5. Mizunoe Y et al. Trehalose protects against oxidative stress by regulating the Keap1-Nrf2 and autophagy pathways. Redox Biol. 15, 115-124 (2017)(PMID:29241092)
  6. Bak DH et al. Anti‑apoptotic effects of human placental hydrolysate against hepatocyte toxicity in vivo and in vitro. Int J Mol Med. 42, 2569-2583 (2018)(PMID:30132515)
  7. Jena KK et al. TRIM16 controls assembly and degradation of protein aggregates by modulating the p62‐NRF2 axis and autophagy. EMBO J. 37, e98358 (2018)(PMID:30143514)
  8. Yamada M et al. p62/SQSTM1 and Nrf2 are essential for exercise-mediated enhancement of antioxidant protein expression in oxidative muscle. FASEB J. 33, 8022-8032 (2019) (PMID:30913396)
  9. Wang Y et al. Activation of PINK1-Parkin-dependent mitophagy in Tri-ortho-cresyl phosphate-treated Neuro2a cells. Chem Biol Interact. 308, 70-79 (2019)(PMID:31100276)
  10. Park JY et al. TFEB activates Nrf2 by repressing its E3 ubiquitin ligase DCAF11 and promoting phosphorylation of p62. Sci Rep. 9, 14354 (2019)(PMID:31586112)

Immunocytochemistry

  1. Watanabe Y et al. HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis. Autophagy 13, 133-148 (2017)(PMID:27846364)

Immunohistochemistry

  1. Watanabe Y et al. HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis. Autophagy 13, 133-148 (2017)(PMID:27846364)
References
  1. Ichimura Y et al. Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol Cell 51,  618-31 (2013)（PMID: 24011591）
  2. Kageyama S et al. Proteasome dysfunction activates autophagy and the keap1-nrf2 pathway. J Biol Chem. 289, 24944-55 (2014)（PMID: 25049227）
Product category
Research area
Autophagy
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 00:05, Apr 19, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.