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HOME > Product search results > Code No. PM059 Anti-KDEL pAb

Code No. PM059

Anti-KDEL pAb

Availability (in Japan)

1-9

(In Japan at 01:30,
Sep 23, 2017 in JST)

Size

100 µL

Data
  • Western Blotting

  • Immunocytochemistry

Clonality Polyclonal Clone Polyclonal
Isotype (Immunized Animal) Rabbit Ig (aff.)
Applications
WB
1:500  
IC
1:1,000  
IH*
reported.  (PMID: 19767744
IF*
reported.  (PMID: 28342860
Immunogen (Antigen) Mouse GRP78 C-terminal 644-654 aa
Reactivity [Gene ID]

Human, Mouse

Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Background The KDEL (lys-asp-glu-leu) sequence is most common endoplasmic reticulum (ER) retention signal. The ER resident proteins, which should be located in the ER, have this retention motif, and this retention is mediated by KDEL receptor. This antibody can specifically detect GRP78 (78 kDa protein) and GRP94 (94 kDa protein) including a KDEL sequence by WB.
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M176-3 Anti-EEA1 mAb
PM062 Anti-EEA1 pAb
M179-3 Anti-GM130 mAb
PM061 Anti-GM130 pAb
M181-3 Anti-KDEL mAb
PM064 Anti-Lamin B1 pAb
PM063 Anti-COX4 pAb
Citations

Immunohistochemistry

  1. Saito A et al. Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nat Cell Biol. 11, 1197-1204 (2009)(PMID:19767744)
  2. Yamanaka T et al. NF-Y inactivation causes atypical neurodegeneration characterized by ubiquitin and p62 accumulation and endoplasmic reticulum disorganization. Nat Commun. 5, 3354 (2014)(PMID:24566496)
  3. Yamanaka T et al. Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS. Sci Rep. 6, 34575 (2016)(PMID:27687130)

Immunofluorescence

  1. Ishii S et al. Functional characterization of lysophosphatidic acid receptor 1 mutants identified in rat cancer tissues. Biochem Biophys Res Commun. 486, 767-773 (2017)(PMID:28342860)
Product category
Tools
Control antibodies
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  • The availability is based on the information in Japan at 01:30, Sep 23, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.