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HOME > Product search results > Code No. MEX004-6 Anti-CD326 (EpCAM) mAb-Biotin

Code No. MEX004-6

Anti-CD326 (EpCAM) mAb-Biotin

Availability (in Japan)

10 or more

(In Japan at 01:30,
Jun 26, 2017 in JST)

Size

50 µg/50 µL

Data
  • Flow Cytometry

  • ELISA

    swCLEIA

  • ELISA

    swCLEIA

Clonality Monoclonal Clone B8-4
Isotype (Immunized Animal) Mouse IgG1 κ
Applications
FCM
5 µg/mL  
ELISA
Can be used. Please refer to "ExoDiluent for Immunoassay (MEX1001)"together.  
Reactivity [Gene ID]

Human[4072]

Storage temp. 4°C Conjugate Biotin Manufacturer MBL
Alternative names ESA, KSA, M4S1, MK-1, DIAR5, EGP-2, EGP40, KS1/4, MIC18, TROP1, EGP314, HNPCC8, TACSTD1
Background The epithelial cell adhesion molecule (EpCAM), also known as a CD326, is a transmembrane glycoprotein and first discovered on human colon carcinoma. In addition, EpCAM is defined as a monoclonal antibody AUA1-reactive cell surface antigen. This type I membrane protein is expressed only on epithelial cells and highly expressed on most carcinoma such as colorectal carcinoma and gastric cancer. EpCAM plays a role in cell-to-cell adhesion by regulating its own homophilic interaction in a Ca2+ independent manner. It is reported that tumor-derived circulating exosomes, called Extracellular Vesicles (EVs) or microvesicles, can be easily isolated using anti-EpCAM antibody bound magnetic beads, followed by various down-stream analyses such as sandwich immunoassay and RT-qPCR to elucidate the tumor-specific exosome surface protein profile and associated miRNA.
Related products MEX002-6 Anti-CD63 (LAMP-3) mAb-Biotin
MEX003-6 Anti-CD81 (TAPA1) mAb-Biotin
MEX001-3 Anti-CD9 mAb
MEX002-3 Anti-CD63 (LAMP-3) mAb
MEX003-3 Anti-CD81 (TAPA1) mAb
MEX-E ExoCap™ Nucleic Acid Elution Buffer
3190 Magnetic Rack
MEX001-6 Anti-CD9 mAb-Biotin
M075-6 Mouse IgG1 (isotype control)-Biotin
EX-EPC-SP ExoCap™ EpCAM Kit for Serum Plasma
D269-3 Anti-EpCAM (CD326) (Mouse) mAb
MEX1001 ExoDiluent for Immunoassay
MEX-SA ExoCap™ Streptavidin Kit
MEX001-4 Anti-CD9 mAb-FITC
MEX002-4 Anti-CD63 (LAMP-3) mAb-FITC
MEX003-4 Anti-CD81 (TAPA1) mAb-FITC
MEX001-12 Anti-CD9 mAb-ALP
MEX002-12 Anti-CD63 (LAMP-3) mAb-ALP
MEX003-12 Anti-CD81 (TAPA1) mAb-ALP
MEX-USB ExoCapTM Ultracentrifugation/Storage Booster
References
  1. Spurr NK et al. Characterization and chromosomal assignment of a human cell surface antigen defined by the monoclonal antibody AUAI. Int J Cancer. 38, 631-6 (1986)(PMID: 3770992
  2. Koga Y et al. Improved recovery of exfoliated colonocytes from feces using newly developed immunomagnetic beads. Gastroenterol Res Pract. 2008, 605273 (2008)(PMID: 19125182
  3. Taylor DD, Gercel-Taylor C. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol. Oncol. 110, 13-21 (2008)(PMID: 18589210
  4. Marhaba R et al. CD44 and EpCAM: cancer-initiating cell markers. Curr Mol Med. 8, 784-804 (2008)(PMID: 19075676
  5. Rabinowits G et al. Exosomal microRNA: a diagnostic marker for lung cancer. Clin Lung Cancer 10, 42-46 (2009)(PMID: 19289371
  6. van der Gun BT et al. EpCAM in carcinogenesis: the good, the bad or the ugly. Carcinogenesis 31, 1913-21 (2010)(PMID: 20837599
Product category
Research area
RNA-RNP Network
Cancer
Cell surface antigens
Exosomes
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 01:30, Jun 26, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.