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HOME > Product search results > Code No. M186-3 Anti-LC3 mAb

Code No. M186-3

Anti-LC3 mAb

Availability (in Japan)

10 or more

(In Japan at 01:30,
Dec 12, 2017 in JST)

Size

100 µg/100 µL

Data
  • Western Blotting

Clonality Monoclonal Clone 8E10
Isotype (Immunized Animal) Mouse IgG2aκ
Applications
WB
1 μg/mL  
Immunogen (Antigen) Human LC3, 1-120 aa Recombinant protein
Reactivity [Gene ID]

Human[81631], Mouse[67443], Rat[64862], Hamster[100769810]

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names microtubule-associated protein 1 light chain 3 beta, LC3B, ATG8F, MAP1LC3B-a, MAP1A/1BLC3, MAP1LC3B
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Notes Clone 8E10 reacts with LC3B and does not cross-react with LC3A, LC3C, GATE-16, and GABARAP.
Citations

Western Blotting

  1. Margariti A et al. XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation. J Biol Chem 288, 859-72 (2013)(PMID:23184933)
  2. Mukai R et al. HTLV-1 HBZ positively regulates the mTOR signaling pathway via inhibition of GADD34 activity in the cytoplasm. Oncogene. 33, 2317-28 (2014)(PMID:23708656)
  3. Maejima Y et al. Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nat Med. 19, 1478-88 (2013)(PMID:24141421)
  4. Wang M et al. EGFR-mediated chromatin condensation protects KRAS-mutant cancer cells against ionizing radiation. Cancer Res. 74, 2825-34 (2014)(PMID:24648348)
  5. He R et al. Divergent roles of BECN1 in LC3 lipidation and autophagosomal function. Autophagy 11, 740-7 (2015)(PMID:25955014)
  6. Hasegawa K et al. Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults. Nat Commun. 7, 10943 (2016)(PMID:26971449)
  7. Li Z et al. Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR. PLoS One 11, e0153526 (2016)(PMID:27077655)
  8. Nakanishi T et al. Relationship between triterpenoid anticancer drug resistance, autophagy, and caspase-1 in adult T-cell leukemia. PeerJ 12, e2026 (2016)(PMID:27190722)
  9. Boada-Romero E et al. The T300A Crohn's disease risk polymorphism impairs function of the WD40 domain of ATG16L1. Nat Commun. 7, 11821 (2016)(PMID:27273576)
  10. Sasaki N et al. Chorein interacts with α-tubulin and histone deacetylase 6, and overexpression preserves cell viability during nutrient deprivation in human embryonic kidney 293 cells. FASEB J. 30, 3726-3732 (2016)(PMID:27468757)
  11. Maueröder C et al. Capability of Neutrophils to Form NETs Is Not Directly Influenced by a CMA-Targeting Peptide. Front Immunol. 8, 16 (2017)  (PMID:28191006)
  12. Zhao Z et al. Curcumin accelerates the repair of sciatic nerve injury in rats through reducing Schwann cells apoptosis and promoting myelinization. Front Immunol. 8, 16 (2017)(PMID:28622711)
  13. He R et al. Glucosyltransferase Activity of Clostridium difficile Toxin B Triggers Autophagy-mediated Cell Growth Arrest. Sci Rep. 7, 10532 (2017)(PMID:28874882)

Immunoprecipitation

  1. Meng XH et al. Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes. Int J Biol Sci. 13, 985-995 (2017)(PMID:28924380)

Immunocytochemistry

  1. Hasegawa K et al. Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults. Nat Commun. 7, 10943 (2016)(PMID:26971449)
  2. Li Z et al. Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR. PLoS One 11, e0153526 (2016)(PMID:27077655)
  3. Meng XH et al. Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes. Int J Biol Sci. 13, 985-995 (2017)(PMID:28924380)
Product category
Research area
Autophagy
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 01:30, Dec 12, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.