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HOME > Product search results > Code No. M062-3 Anti-SOD1 (Human) mAb

Code No. M062-3

Anti-SOD1 (Human) mAb

Availability (in Japan)

1-9

(In Japan at 01:30,
Nov 24, 2017 in JST)

Size

100 µg/100 µL

Data
  • Western Blotting

Clonality Monoclonal Clone 1G2
Isotype (Immunized Animal) Mouse IgG1 κ
Applications
WB
1 μg/mL  
IH*
reported.  (PMID: 27264390 / 28057013
Immunogen (Antigen) Recombinant Human full-length SOD1
Reactivity [Gene ID]

Human[6647], Mouse(-), Rat(-)

Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names superoxide dismutase 1
Related products M200-3MS Anti-NRF2 mAb for My select sampler set
M200-3 Anti-NRF2 mAb
Citations

Western Blotting

  1. Hashimoto Y et al. A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta. PNAS 98, 6336-41 (2001)(PMID:11371646)
  2. Hashimoto Y et al. The Gtx homeodomain transcription factor exerts neuroprotection using its homeodomain. J. Biol. Chem. 279, 16767-77 (2004)(PMID:14754886)
  3. Kanekura K et al. Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants. J Biol Chem. 279, 19247-56 (2004)(PMID:14970233)
  4. Schonhoff CM et al. S-nitrosothiol depletion in amyotrophic lateral sclerosis. PNAS 103, 2404-9 (2006)(PMID:16461917)
  5. Nawa M et al. A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB. Cell Signal. 20, 493-505 (2008)(PMID:18160256)
  6. Doi K et al. Mitochondrial changes in motor neurons of homozygotes of leucine 126 TT deletion SOD1 transgenic mice. Neuropathology 28, 269-76 (2008)(PMID:18179411)
  7. Ren G et al. Cu, Zn-superoxide dismutase 1 (SOD1) is a novel target of Puromycin-sensitive aminopeptidase (PSA/NPEPPS): PSA/NPEPPS is a possible modifier of amyotrophic lateral sclerosis. Mol. Neurodegener. 6, 29 (2011)(PMID:21548977)
  8. Hineno A et al. Distinctive clinicopathological features of 2 large families with amyotrophic lateral sclerosis having L106V mutation in SOD1 gene. J Neurol Sci. 319, 63-74 (2012)(PMID:22647583)

Immunohistochemistry

  1. Morisaki Y et al. Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9. Sci Rep. 6, 27354 (2016)(PMID:27264390)
  2. Tokuda E et al. Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis. Mol Neurodegener. 12, 2 (2017)(PMID:28057013)
Product category
Research area
Neuroscience
Cellular stress
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 01:30, Nov 24, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.