Anti-PML (Human) mAb

Availability (in Japan)

10 or more

（In Japan at 17:00,
Apr 16, 2024 in JST）

Size

100 µL (1 mg/mL)

Citations

Data Sheet

SDS

Data	Western Blotting Flow Cytometry Immunocytochemistry
Clonality	Monoclonal	Clone	1B9
Isotype (Immunized Animal)	Mouse IgG1
Applications	WB 10 µg/mL IP* reported. （PMID: 15331439） FCM 10 µg/mL IC 1 µg/mL
Immunogen (Antigen)	Recombinant Human full length PML
Reactivity [Gene ID]	Human[5371]
Storage buffer	1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp.	-20°C	Conjugate	Unlabeled	Manufacturer	MBL
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Citations	Yung TM et al. Cellular dynamics of the negative transcription elongation factor NELF. Exp Cell Res. 315, 1693-705 (2009)(PMID:19245807) Western Blotting Qiu F et al. Knockdown of endogenous RNF4 exacerbates ischaemia-induced cardiomyocyte apoptosis in mice. J Cell Mol Med. 24, 9545-9559 (2020)(PMID:32722882) Immunoprecipitation Nguyen LA, et al., Physical and functional link of the leukemia-associated factors AML1 and PML. Blood. 105, 292-300 (2005)(PMID:15331439) Yoshida H et al. PML-retinoic acid receptor alpha inhibits PML IV enhancement of PU.1-induced C/EBPepsilon expression in myeloid differentiation. Mol Cell Biol. 27, 5819-34 (2007)(PMID:17562868) Tagata T et al. Phosphorylation of PML is essential for activation of C/EBP epsilon and PU.1 to accelerate granulocytic differentiation. Leukemia. 22, 273-80 (2008)(PMID:17989726) Immunocytochemistry Al Rashid ST, et al., Evidence for the direct binding of phosphorylated p53 to sites of DNA breaks in vivo. Cancer Res. 65, 10810-21. (2005)(PMID:16322227)
Product category	Research area RNA-RNP Network Epigenetics Cancer

The availability is based on the information in Japan at 17:00, Apr 16, 2024 in JST.
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Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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