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HOME > Product search results > Code No. K0039-3 Anti-CD120a (TNF-R1) (Human) mAb

Code No. K0039-3

Anti-CD120a (TNF-R1) (Human) mAb

Availability (in Japan)

10 or more

(In Japan at 00:05,
Nov 15, 2018 in JST)

Size

100 µg/100 µL

Data
  • Flow Cytometry

Clonality Monoclonal Clone H398
Isotype (Immunized Animal) Mouse IgG2a
Applications
FCM
10 µg/mL (final concentration)  
Immunogen (Antigen) affinity-purified TNF receptor derived from HL-60
Reactivity [Gene ID]

Human[7132]

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names TNFRSF1A, TNFR1
Background Tumor necrosis factor receptor 1 (TNF-R1/CD120a) is a member of TNF receptor family, includes Fas/Apo1 (CD95), CD30, OX40 (CD134), and 4-1BB (CD137), which are characterized by cysteine rich motifs in the extracellular domain. TNF-R1 contains an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF-R1 associated death domain protein), and subsequent interactions with FADD. TNF-R1 can also activate the transcription factor NF-κB via TRAF2 (TNF receptor associated factor 2). The cytoplasmic domain of TNF-R1 can directly interact with Jak kinase, thereby activating the JAK/STAT signal transduction cascade.
Related products D113-3 Anti-TNF-α (Human) mAb
D114-3 Anti-TNF-β (Lymphotoxin) (Human) mAb
W072-3 Anti-CD358 (DR6) (Human) mAb
K0040-3 Anti-CD120b (TNF-R2) (Human) mAb
K0039-4 Anti-CD120a (TNF-R1) (Human) mAb-FITC
K0040-4 Anti-CD120b (TNF-R2) (Human) mAb-FITC
Product category
Research area
Cell surface antigens
Cytokine & Growth Factors
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 00:05, Nov 15, 2018 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.