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HOME > Product search results > Code No. D205-3 Anti-TLR4 (CD284) (Mouse) mAb

Code No. D205-3

Anti-TLR4 (CD284) (Mouse) mAb

Availability (in Japan)

1-9

(In Japan at 01:30,
Oct 19, 2017 in JST)

Size

100 µg/100 µL

Data
  • Flow Cytometry

Clonality Monoclonal Clone UT49
Isotype (Immunized Animal) Mouse IgG2b
Applications
IP*
reported.  (PMID: 18158784
FCM
5 µg/mL (final concentration)  
Immunogen (Antigen) Mouse TLR4-MD-2 transfected Ba/F3 cells
Reactivity [Gene ID]

Mouse[21898]

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names toll-like receptor 4, Lps, Ly87, Ran/M1, Rasl2-8
Background Toll, a Drosophila receptor molecule with extracellular leucine-rich repeat (LRR), has a role in triggering innate defenses against bacteria or fungi. TLR4 (Toll-like receptor 4) is a member of TLR family, which is human homologue of Toll protein. It has extracellular LRR and an intracellular signaling domain, which is similar to the type I IL-1 receptor. TLR4 is expressed in subpopulations of cells including myeloid cells, B-cells, monocytes, and endothelial cells. Recent studies have suggested that TLR4 might act as a receptor for LPS (lipopolysaccharide). TLR4 alone is not capable of sensing and signaling the presence of LPS, but another molecule MD-2, which is physically associated with TLR4, is required for LPS recognition through TLR4.
Related products D077-4 Anti-TLR4 (CD284) (Human) mAb-FITC
K0212-3 Anti-TLR2 (CD282) mAb
K0213-3 Anti-TLR9 (CD289) mAb
D205-4 Anti-TLR4 (CD284) (Mouse) mAb-FITC
D206-3 Anti-TLR4-MD-2 complex (Mouse) mAb
D206-5 Anti-TLR4-MD-2 complex (Mouse) mAb-PE
D077-3 Anti-TLR4 (CD284) (Human) mAb
D077-5 Anti-TLR4 (CD284) (Human) mAb-PE
D079-3 Anti-TLR4-MD-2 complex (Mouse) mAb
D079-4 Anti-TLR4-MD-2 complex (Mouse) mAb-FITC
D079-5 Anti-TLR4-MD-2 complex (Mouse) mAb-PE
M077-4 Mouse IgG2b (isotype control)-FITC
Citations
  1. Kozako T et al. Efficient induction of human T-cell leukemia virus-1-specific CTL by chimeric particle without adjuvant as a prophylactic for adult T-cell leukemia. Mol Immunol. 47, 606-13 (2009)(PMID:19889459)
References
  1. Bahrun U et al. Preparation and characterization of agonistic monoclonal antibodies against Toll-like receptor 4-MD-2 complex. Hybridoma 26, 393-9 (2007)(PMID: 18158784
Product category
Research area
Immunology
Cell surface antigens
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 01:30, Oct 19, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.