This site is for customers in Asia. Customers in China & other regions, please go to Global page.
HOME > Product search results > Code No. D092-3M2 Anti-CD274 (PD-L1) (Human) mAb (Functional Grade)

Code No. D092-3M2

Anti-CD274 (PD-L1) (Human) mAb (Functional Grade)

Availability (in Japan)

10 or more

(In Japan at 01:30,
Dec 14, 2017 in JST)

Size

100 µg/100 µL

Data
  • Flow Cytometry

Clonality Monoclonal Clone MIH3
Isotype (Immunized Animal) Mouse IgG1
Applications
FCM
5-10 µg/mL  
Other(Adhesion Assay )
reported.  (PMID: 18585785
Immunogen (Antigen) L cells transfected full length human PD-L1 protein
Reactivity [Gene ID]

Human[29126]

Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
Background Programmed death ligand 1 (PD-L1, also known as CD274/B7-H1), a member of B7 family was identified by searching for molecules that share homology with the immunogloblin V and C domains of B7-1 and B7-2 among the human cDNA expressed sequence tags in the National Center for Biotechnology Information database. PD-L1 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA4 subfamily. Although in vitrostudy indicated that the cross-linking of PD-1 by PD-L1 leads to down-regulation of T-cell responses, some studies have shown that T cells stimulated with low levels of anti-CD3 and immobilized PD-L1-Ig were activated, proliferation and production of IFN-g GM-CSF and IL-10 from the T cells were enhanced. The role of PD-L1 is now debatable.
Related products D092-3 Anti-CD274 (PD-L1) (Human) mAb
D092-6 Anti-CD274 (PD-L1) (Human) mAb-Biotin
D230-3 Anti-CD274 (PD-L1) (Human) mAb
D230-5 Anti-CD274 (PD-L1) (Human) mAb-PE
D133-3M2 Anti-CD279 (PD-1) (Human) mAb (Functional Grade)
M075-3M2 Mouse IgG1 (isotype control) (Functional Grade)
Product category
Research area
Immunology
Cell surface antigens
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 01:30, Dec 14, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.