Code No. D077-4
Anti-TLR4 (CD284) (Human) mAb-FITC
Availability (in Japan)
1-9
（In Japan at 00:05,
Aug 22, 2018 in JST）
Size
1 mL (50 tests)
Data Sheet| Clonality | Monoclonal | Clone | HTA125 | ||
|---|---|---|---|---|---|
| Isotype (Immunized Animal) | Mouse IgG2a | ||||
| Applications |
|
||||
| Immunogen (Antigen) | human TLR4 transfected cells | ||||
| Reactivity [Gene ID] | Human |
||||
| Storage buffer | 80 µg/mL IgG inPBS/1% BSA/0.09% NaN3 | ||||
| Storage temp. | ４°C | Conjugate | FITC | Manufacturer | MBL |
| Background | Toll, a Drosophila receptor molecule with extracellular leucine-rich repeat (LRR), has a role in triggering innate defenses against bacteria or fungi. Toll-like receptor 4 (TLR4/CD284) is a member of TLR family, which is human homologue of Toll protein. It has extracellular LRR and an intracellular signaling domain, which is similar to the type I IL-1 receptor. TLR4 is expressed in subpopulations of cells including myeloid cells, B cells, monocytes, and endothelial cells. Recent studies have suggested that TLR4 might act as a receptor for lipopolysaccharide (LPS). TLR4 alone is not capable of sensing and signaling the presence of LPS, but another molecule MD-2, which is physically associated with TLR4, is required for LPS recognition through TLR4. |
||||
| Related products | D077-3 Anti-TLR4 (CD284) (Human) mAb D077-5 Anti-TLR4 (CD284) (Human) mAb-PE D205-3 Anti-TLR4 (CD284) (Mouse) mAb D205-4 Anti-TLR4 (CD284) (Mouse) mAb-FITC PD047 Anti-TLR8 (CD288) (Human) pAb K0212-3 Anti-TLR2 (CD282) mAb K0213-3 Anti-TLR9 (CD289) mAb |
||||
| Product category |
|
||||
- The availability is based on the information in Japan at 00:05, Aug 22, 2018 in JST.
- The special price is shown in red color.
- Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
- Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation - For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
- For storage temparature: RT: room temparature
- Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.