Kit, protein, vector, etc detailed product information

Code No.	CY-8150
CircuLex PCSK9-LDLR in vitro Binding Assay Kit
Price	¥107,800
Size	96 assays
Availability (in Japan)	1-9 （In Japan at 17:00, Apr 20, 2024 in JST）
Components	Microplate, Recombinant His-tagged PCSK9 wild type, Biotinylated anti-His-tag monoclonal antibody, Reaction Buffer, HRP-conjugated Streptavidin, Conjugate Dilution Buffer, 10X Wash Buffer, Substrate Reagent, Stop Solution
Intended use	This Kit is primarily designed to screening inhibitors of PCSK9-LDLR interaction in vitro.
Storage temp.	4°C
Manufacturer	MBL
Related products	CY-8078 CircuLex Mouse/Rat PCSK9 ELISA Kit CY-8079 CircuLex Human PCSK9 ELISA Kit CY-R2311 PCSK9 D374Y in culture medium CY-R2330 PCSK9 Wild Type (Human) CY-R2331 PCSK9 D374Y CY-R2333 PCSK9 R194A CY-R2340 LDLR EGF-AB domain CY-8153 CircuLex Human PCSK9 Functional Assay Kit
Product category	Research area:Metabolism Drug discovery
Citations	Lammi C et al. Lupin peptides modulate the protein-protein interaction of PCSK9 with the low density lipoprotein receptor in HepG2 cells. Sci Rep. 6, 29931 (2016)(PMID:27424515) Lammi C et al. Biological Characterization of Computationally Designed Analogs of peptide TVFTSWEEYLDWV (Pep2-8) with Increased PCSK9 Antagonistic Activity. Sci Rep. 9, 2343 (2019)(PMID:30787312) Evison BJ et al. A Small Molecule Inhibitor of PCSK9 That Antagonizes LDL Receptor Binding via Interaction With a Cryptic PCSK9 Binding Groove. Bioorg Med Chem. 28, 115344 (2020)(PMID:32051094)

The availability is based on the information in Japan at 17:00, Apr 20, 2024 in JST.
The special price is shown in red color.
Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
For storage temparature: RT: room temparature
Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.