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HOME > Product search results > Code No. CY-1151V2 CycLex® SIRT1/Sir2 Deacetylase Fluorometric Assay Kit Ver.2

Code No. CY-1151V2

CycLex® SIRT1/Sir2 Deacetylase Fluorometric Assay Kit Ver.2

Price

¥70,400

Availability (in Japan)

0
(Contact us)

(In Japan at 00:05,
Apr 20, 2024 in JST)

Size

100 assays

Data
  • Effect of Trichostatin A and NAD on recombinant SIRT1 activity

    Effect of Trichostatin A and NAD on recombinant SIRT1 activity

Components SIRT1 Assay Buffer, Fluoro-Substrate Peptide (0.2 mM), Fluoro-Deacetylated Peptide (0.2 mM), NAD (2 mM), Developer, Recombinant SIRT1, Stop Solution
Intended use This kit is designed for the rapid and sensitive evaluation of SIRT1/Sir2
inhibitors or activators using crude SIRT1/Sir2 fraction or purified SIRT1/Sir2.
Storage temp. -80°C Manufacturer MBL
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Citations
  1. Kayashima Y et al. Alkylresorcinols activate SIRT1 and delay ageing in Drosophila melanogaster. Sci Rep. 7, 43679 (2017)(PMID:28252007)
  1. Peng J et al. Quercetin Improves Glucose and Lipid Metabolism of Diabetic Rats: Involvement of Akt Signaling and SIRT1. J Diabetes Res. 2017, 3417306 (2017)(PMID:29379801)
  1. Conti V et al. SIRT1 Activity in Peripheral Blood Mononuclear Cells Correlates with Altered Lung Function in Patients with Chronic Obstructive Pulmonary Disease. Oxid Med Cell Longev. 2018, 9391261 (2018)(PMID:29861836)
  1. Shigemoto R et al. 5-Methylmellein is a novel inhibitor of fungal sirtuin and modulates fungal secondary metabolite production. J Gen Appl Microbiol. (2018) In press.(PMID:29794367)
  1. Corbi G et al. Phenolic Plant Extracts Induce Sirt1 Activity and Increase Antioxidant Levels in the Rabbit's Heart and Liver. Oxid Med Cell Longev. 2018, 2731289 (2018)(PMID:30116475)
  1. Corbi G et al. Cardiac Rehabilitation Increases SIRT1 Activity and β-Hydroxybutyrate Levels and Decreases Oxidative Stress in Patients with HF with Preserved Ejection Fraction. Oxid Med Cell Longev. 2019, 7049237 (2019) (PMID:31885811)
  1. Chiang S et al. The potential of the novel NAD+ supplementing agent, SNH6, as a therapeutic strategy for the treatment of Friedreich's ataxia. Pharmacol Res.155, 104680 (2020)(PMID:32032665)

ELISA

  1. Xu S et al. Evidence for SIRT1 Mediated HMGB1 Release From Kidney Cells in the Early Stages of Hemorrhagic Shock. Front Physiol. 854, 10. 854 (2019)(PMID:31333497)

Other

  1. Yaku K et al. Metabolism and biochemical properties of nicotinamide adenine dinucleotide (NAD) analogs, nicotinamide guanine dinucleotide (NGD) and nicotinamide hypoxanthine dinucleotide (NHD).Sci Rep. 9, 13102 (2019)(PMID:31511627)
Product category
Research area
Cancer
Drug discovery
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