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HOME > Product search results > Code No. CY-1163 CycLex® Polo-like kinase 1 Assay/Inhibitor Screening Kit

Code No.　CY-1163

CycLex® Polo-like kinase 1 Assay/Inhibitor Screening Kit

Price

¥110,000

Availability (in Japan)

0
(Contact us)

（In Japan at 17:00,
Apr 16, 2024 in JST）

Size

96 assays

Components Microplate (coated with recombinant Protein-X as Polo-like kinase 1 substrate), 10X Wash Buffer Kinase Buffer, 20X ATP, Anti-Phospho-Serine/Threonine Monoclonal Antibody(PTS-07) Substrate Reagent, HRP conjugated Anti-mouse IgG, Stop Solution
Intended use This Kit is designed to measure the activities of purified polo-like kinase 1 (Plk1) for the rapid and sensitive evaluation of inhibitors using recombinant Plk1.
Storage temp. 4°C Manufacturer MBL
Related products CY-E1163 Plk1 positive control
Citations
  1. Hyo-Eun Yoon, Soo-A Kim, Hong Seok Choi, Mee-Young Ahn, Jung-Hoon Yoon, Sang-Gun Ahn; Inhibition of Plk1 and Pin1 by 5’-nitro-indirubinoxime suppresses human lung cancer cells. Cancer Letters. 316: 97-104. 2012(PMID:22115795)
  1. Kim SM et al. Enhanced cellular uptake of a TAT-conjugated peptide inhibitor targeting the polo-box domain of polo-like kinase 1. Amino Acids. 46, 2595-603 (2014)(PMID:25151148)
  1. Srinivasrao G et al. Design and synthesis of a cell-permeable, drug-like small molecule inhibitor targeting the polo-box domain of polo-like kinase 1. PLoS One. 9, e107432 (2014)(PMID:25211362)
  1. Morris EJ et al. A Model of Differential Mammary Growth Initiation by Stat3 and Asymmetric Integrin-α6 Inheritance. Cell Rep. 30, 3605-3615.e5 (2020)(PMID:32187533)
Product category
Research area
Cancer
Drug discovery
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