Caspase inhibitor Z-VAD-FMK

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1. Sagiv A et al. Granule exocytosis mediates immune surveillance of senescent cells. Oncogene 32, 1971–1977 (2013)(PMID:26935269)

1. Wang C et al. A bead-based cleavage method for large-scale identification of protease substrates. Sci Rep. 6, 22645 (2016)(PMID:26935269)

1. Kitazawa M et al. ASC Induces Apoptosis via Activation of Caspase-9 by Enhancing Gap Junction-Mediated Intercellular Communication. PLoS One. 12, e0169340 (2017)(PMID:28056049)

1. Tokunaga E et al. Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others. PLoS One. 12, e0182152 (2017)(PMID:28763493)

1. Hsu JM et al. STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion. Nat Commun. 9, 1908 (2018)(PMID:29765039)

1. Kozako T et al. The small molecule STF-62247 induces apoptotic and autophagic cell death in leukemic cells. Oncotarget 9, 27645-27655 (2018)(PMID:29963226)

1. Kozako T et al. Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines. BMC Cancer. 18, 791 (2018)(PMID:30081901)

1. Hirasawa M, Kurita-Ochiai T. Porphyromonas gingivalis Induces Apoptosis and Autophagy via ER Stress in Human Umbilical Vein Endothelial Cells. Mediators Inflamm. 2018, 1967506 (2018)(PMID:30150893)

1. Zhang E et al. The functional role of Bax/Bak in palmitate-induced lipoapoptosis. Food Chem Toxicol. 123, 268-274 (2019)(PMID:30408539)

1. Sanjo H et al. Cutting Edge: TAK1 Safeguards Macrophages against Proinflammatory Cell Death. J Immunol. 203, 783-788 (2019)(PMID:31243089)

1. Matsuo K et al. Delta-like 3 localizes to neuroendocrine cells and plays a pivotal role in gastrointestinal neuroendocrine malignancy. Cancer Sci. 110, 3122-3131 (2019)(PMID:31369178)

1. Sasaki K et al. Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death. Nat Commun. 10, 3878 (2019)(PMID:31462647)

Function

1. Hoshi T et al. Lenvatinib induces death of human hepatocellular carcinoma cells harboring an activated FGF signaling pathway through inhibition of FGFR-MAPK cascades. Biochem Biophys Res Commun. 513, 1-7 (2019)(PMID:30944079)
2. Aoki K et al. Coordinated changes in cell membrane and cytoplasm during maturation of apoptotic bleb. Mol Biol Cell. 31, 833-844 (2020)(PMID:32049595)

1. Slee EA et al. Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32. Biochem J. 315, 21-24 (1996)（PMID: 8670109）