Code No. | RN014MW | Print out |
Anti-SFPQ (PSF) mAb | ||
Price | ¥48,000 | |
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 00:05, Mar 29, 2024 in JST) |
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Clonality | Monoclonal | |
Clone | C23 | |
Isotype (Immunized Animal) |
Mouse IgG2aκ | |
Applications | WB 1 µg/mL IP 2 µg/sample IC 0.5 µg/mL IH 1 µg/mL |
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Immunogen (Antigen) |
KLH-conjugated synthetic peptide, CAGYGRGREEYEGPNKKPRF (corresponding to amino acid residues 681-699 of mouse Sfpq) | |
Reactivity [Gene ID] | ||
Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | POMP100, PPP1R140 | |
Background | Paraspeckle is one of newly identified subnuclear bodies consists of RNAs and RNA-binding proteins. SFPQ, also known as PSF, is a core component of paraspeckle and belongs to DBHS protein family. SFPQ forms heteromer by binding to other DHBS protein family, such as p54/NONO, and participates in mRNA splicing and transcriptional regulation in the nucleus. In Alzheimer's and Pick's diseases known as tauopathy, SFPQ is accumulated in cytoplasm in neurons and astrocytes. Altered localization of SFPQ together with tau mutation may be involved in pathogenesis of neurodegenerative diseases. | |
Related products | RN013MW Anti-Nono (P54NRB) mAb RN092PW Anti-NONO (P54NRB) pAb M019-3 Anti-Nucleolin mAb M041-3 Anti-PML (Human) mAb PM064 Anti-Lamin B1 pAb PM091 Anti-Per1 (Mouse) pAb PM093 Anti-NR1D2 (Rev-erbβ) pAb |
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Product category | Research area:RNA-RNP Network Epigenetics Brands:RiboCluster Profiler™ |
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Data | ||
Citations | Western Blotting
Immunocytochemistry
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References |
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