Code No. | RN004P | |
Anti-ELAVL1 (HuR) pAb | ||
Price | ¥66,000 | |
Size | 200 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 17:33, Apr 26, 2024 in JST) |
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Clonality | Polyclonal | |
Clone | Polyclonal | |
Isotype (Immunized Animal) |
Rabbit Ig (aff.) | |
Applications | WB 1:1,000 IP 5 µg/250 µL of cell extract from 2.5 x 106 cells IC Can be used. RIP 15 µg/500 µL of cell extract from 1.5 x 107 cells |
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Immunogen (Antigen) |
KLH-conjugated synthetic peptide MSNGYEDHMAEDCRGDIGR (1-19 aa) | |
Reactivity [Gene ID] | Human[1994](PMID: 23176121), Mouse[15568], Rat[363854], Hamster[100754131] |
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Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R), HUR, Hua, MelG, ELAV1/HUR, W91709, 2410055N02Rik | |
Background | ELAVL1/HuR, like other ELAVL proteins, has a short N-terminal region followed by 2 RNA-binding motifs, a basic linker domain, and a third RNA-binding motif. The basic hinge region bears a novel nuclear shuttling sequence which is implicated in the nucleocytoplasmic HuR shuttling. Unlike its neuron-specific ELAV relatives (HuB, HuC and HuD), HuR itself is ubiquitously expressed. Structure-function analyses of HuR have shown that it binds to AU-rich mRNA sequences in the nucleus and may be involved in their nuclear export. | |
Related products | RN1001 RIP-Assay Kit RN1005 RIP-Assay Kit for microRNA RN005P Anti-ELAVL2 (HuB) (Human) pAb RN006P Anti-ELAVL3 (HuC) pAb RN007M Anti-ELAVL1 (HuR) mAb |
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Product category | Research area:RNA-RNP Network Cancer Brands:RiboCluster Profiler™ |
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Data | ||
Citations | Western Blotting
RNP Immunoprecipitation
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