Antibody detailed product information

Code No. MEX003-4 プリントPrint out
Anti-CD81 (TAPA1) mAb-FITC
Price ¥32,000
Size 50 µg/100 µL
Availability (in Japan) 10 or more
(In Japan at 17:00, Sep 21, 2019 in JST)
Clonality Monoclonal
Clone A103-10
Isotype
(Immunized Animal)
Mouse IgG2aκ
Applications FCM 5 µg/mL (final concentration)  
Immunogen
(Antigen)
human prostate carcinoma cell line (PC3) derived exosomes (prepared by ultracentrifugation from cultured supernatant)
Reactivity [Gene ID]

Human[975]

Storage buffer 500 µg/mL in PBS containing 1% BSA and 0.1% ProClin 150
Storage temp. 4°C
Conjugate FITC
Manufacturer MBL
Alternative names CVID6, S5.7, TSPAN28
Background CD81 antigen, also known as TAPA1, is a tetraspanin characterized by four transmembrane domains and a member of the transmembrane 4 superfamily. CD81 has broad tissue distribution and may play multiple roles in a variety of cellular processes such as immune response and tumorigenesis, but its function has not been elucidated entirely. It is reported that the tetraspanins CD9, CD63 and CD81 are highly enriched on a certain type of extracellular vesicles, called exosome. Because of various exosome features, CD81, one of the representative exosome surface proteins, is thought to be related to cell-cell communication.
Related products MEX001-4 Anti-CD9 mAb-FITC
MEX002-4 Anti-CD63 (LAMP-3) mAb-FITC
MEX001-3 Anti-CD9 mAb
MEX002-3 Anti-CD63 (LAMP-3) mAb
MEX003-3 Anti-CD81 (TAPA1) mAb
MEX001-6 Anti-CD9 mAb-Biotin
MEX002-6 Anti-CD63 (LAMP-3) mAb-Biotin
MEX003-6 Anti-CD81 (TAPA1) mAb-Biotin
MEX004-6 Anti-CD326 (EpCAM) mAb-Biotin
M076-4 Mouse IgG2a (isotype control)-FITC
MEX001-12 Anti-CD9 mAb-ALP
MEX002-12 Anti-CD63 (LAMP-3) mAb-ALP
MEX003-12 Anti-CD81 (TAPA1) mAb-ALP
Product category Research area:Cancer Cell surface antigens Exosomes
Data

References
  1. Simons M, Raposo G. Exosomes--vesicular carriers for intercellular communication. Curr Opin Cell Biol. 21, 575-81 (2009)(PMID: 19442504
  2. Pols MS, Klumperman J, Trafficking and function of the tetraspanin CD63. Exp Cell Res. 315, 1584-92 (2009)(PMID: 18930046
  3. Yoshioka Y et al. Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen. Nat Commun. 5, 3591 (2014)(PMID: 24710016
  4. Melo SA et al. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature 523, 177-82 (2015)(PMID: 26106858
  • The availability is based on the information in Japan at 17:00, Sep 21, 2019 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
MBLCopyright (C)2015 Medical & Biological Laboratories Co., Ltd. All Rights Reserve