Code No. | K0204-3 | Print out |
Anti-Txnip (VDUP1) mAb | ||
Price | ¥30,000 | |
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 17:00, Mar 28, 2024 in JST) |
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Clonality | Monoclonal | |
Clone | JY1 | |
Isotype (Immunized Animal) |
Mouse IgG2b | |
Applications | WB 10 μg/mL IP 2 μg/200 μL of cell extract from 5x106 cells |
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Immunogen (Antigen) |
Recombinant Human Txnip/VDUP1 | |
Reactivity [Gene ID] | ||
Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | thioredoxin interacting protein, THIF, HHCPA78, EST01027/THIF, Tbp-2, Hyplip1, AA682105, 1200008J08Rik | |
Background | Thioredoxin (TRX)-binding protein (Txnip), also called Vitamin D3 up-regulated protein 1 (VDUP1) is an endogenous inhibitor of TRX. Redox-dependent regulation of Txnip by mitogenic factors through Reactive oxygen species (ROS) and the specific binding of Txnip to the redox-sensitive cysteine-sulfide center of TRX modulate intracellular levels of ROS and the mitogenic activity of TRX. It has been reported that Txnip plays important roles in diverse cellular processes, including the regulation of cellular redox balance, apoptosis, proliferation, and differentiation. | |
Related products | K0205-3 Anti-Txnip (VDUP1) mAb M013-3 Anti-Thioredoxin (Trx-tag) mAb |
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Product category | Research area:Cellular stress | |
Data | ||
Citations |
Western Blotting
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