Antibody detailed product information
| Code No. | D370-3H | |
| Anti-HLA class I (HLA-A,B,C) (Human) mAb | ||
| This antibody (clone EMR8-5.1) is validated with automated slide stainers. | ||
| Price | ¥35,200 | |
| Size | 6 mL | |
| Availability (in Japan) | 10 or more
（In Japan at 00:05, Apr 20, 2024 in JST） |
|
| Clonality | Monoclonal | |
| Clone | EMR8-5.1 | |
| Isotype (Immunized Animal) |
Mouse IgG1 κ | |
| Applications | IH Ready for use. (Heat treatment is necessary for paraffin-embedded sections.) |
|
| Immunogen (Antigen) |
Recombinant HLA-A*24:02 extracellular domain | |
| Reactivity [Gene ID] | ||
| Storage buffer | PBS/1% BSA/0.09% NaN3 | |
| Storage temp. | 4°C | |
| Conjugate | Unlabeled | |
| Manufacturer | MBL | |
| Alternative names | pan-HLA | |
| Background | Human major histocompatibility complex (MHC) class I antigen-epitope peptide complex associated with β2-microglobulin are expressed by all human nucleated cells. It plays an important role in cell-mediated immune responses. Abnormalities in MHC class I antigen surface expression are frequently found in malignancies and infectious diseases. They are often associated with reduced recognition by MHC class I antigen-restricted, tumor or virus-associated antigen-specific cytotoxic T lymphocytes and disease progression. The EMR8-5.1 monoclonal antibody reacts with a non-polymorphic epitope of human MHC class I antigens, HLA-A, -B, and -C. This antibody is suitable for study of MHC class I down-regulation using routine formalin-fixed paraffin-embedded sections by immunohistochemistry. | |
| Related products | D367-3 Anti-HLA class I (HLA-A,B,C) (Human) mAb |
|
| Product category | Research area:Immunology Cancer | |
| Data |    |
|
- The availability is based on the information in Japan at 00:05, Apr 20, 2024 in JST.
- The special price is shown in red color.
- Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
- Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization - For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
- For storage temparature: RT: room temparature
- Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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