Code No. | D186-3 | |
Anti-Granulysin (Human) mAb | ||
Price | ¥52,800 | |
Size | 100 µL (1 mg/mL) | |
Availability (in Japan) | 10 or more
(In Japan at 17:00, May 11, 2024 in JST) |
|
Clonality | Monoclonal | |
Clone | RF10 | |
Isotype (Immunized Animal) |
Mouse IgG2aκ | |
Applications | WB 1 µg/mL IP 5 µg/200 µL of cell extract from 5x106 cells FCM 5-10 µg/mL (final concentration) IC 2-5 µg/mL IH* (PMID: 27421110 / 28027826) |
|
Immunogen (Antigen) |
full-length human Granulysin expressing plasmids | |
Reactivity [Gene ID] | Human[10578] |
|
Storage buffer | 1 mg/mL in PBS/50% glycerol, pH 7.2 | |
Storage temp. | -20°C | |
Conjugate | Unlabeled | |
Manufacturer | MBL | |
Alternative names | GNLY | |
Background | Granulysin is an antimicrobial protein expressed on cytotoxic T cells, natural killer (NK) cells and NKT cells. It has been shown that Granulysin contributes to the defence mechanisms against variety of mycobacterial infection and tumors. Granulysin has two molecular forms, 15-kDa precursor and 9-kDa effector form. There serum levels were significantly elevated during the acute viral infections and correlated with the NK cell and CTL activities in patients with sever immunodeficiency, indicate that serum Granulysin could be useful novel marker to evaluate the overall status of host cell immunity. | |
Related products | D185-3 Anti-Granulysin (Human) mAb D185-6 Anti-Granulysin (Human) mAb-Biotin D184-3 Anti-Granulysin (Human) mAb |
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Product category | Research area:Immunology Apoptosis | |
Data | ||
Citations | Western Blotting
Flow Cytometry
Immunocytochemistry
Immunohistochemistry
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