Code No. |
D046-3 |
Anti-IL-18 (Mouse) mAb
|
Price |
¥52,800
|
Size |
100 µL (1 mg/mL) |
Availability (in Japan) |
10 or more
(In Japan at 17:33, Apr 26, 2024 in JST)
|
Clonality |
Monoclonal |
Clone |
39-3F |
Isotype
(Immunized Animal) |
Rat IgG2a |
Applications |
WB 1 μg/mL Function* reported. (PMID: 11145690)
|
Immunogen
(Antigen) |
Recombinant Mouse IL-18 |
Reactivity [Gene ID] |
Human(-), Mouse[16173] |
Storage buffer |
1 mg/mL in PBS/50% glycerol, pH 7.2 |
Storage temp. |
-20°C |
Conjugate |
Unlabeled |
Manufacturer |
MBL |
Alternative names |
interleukin 18 (interferon-gamma-inducing factor), IGIF, IL1F4, IL-1g |
Related products |
D047-3 Anti-IL-18 (Mouse) mAb D048-3 Anti-IL-18 (Mouse) mAb D043-3 Anti-IL-18 (Human) mAb D044-3 Anti-IL-18 (Human) mAb D045-3 Anti-IL-18 (Human) mAb PM014 Anti-IL-18 (Human) pAb M157-3 Anti-IL-18 (Rat) mAb M158-3 Anti-IL-18 (Rat) mAb D048-3M2 Anti-IL-18 (Mouse) mAb (Functional Grade) 7625 Mouse IL-18 ELISA Kit D048-6 Anti-IL-18 (Mouse) mAb-Biotin PD039 Anti-cleaved IL-1β (Mouse) pAb D358-3 Anti-IL-38 (IL1F10) (Human) mAb D359-3 Anti-IL-38 (IL1F10) (Human) mAb
|
Product category |
Research area:Immunology Cytokine & Growth Factors |
Data |
|
Citations |
Western Blotting - Hoshino T et al. Cutting edge: IL-18-transgenic mice: in vivo evidence of a broad role for IL-18 in modulating immune function. J Immunol. 166, 7014-8 (2001)(PMID:11390444)
- Seino H et al. IL-18 mediates the formation of stress-induced, histamine-dependent gastric lesions. Am J Physiol Gastrointest Liver Physiol. 292, G262-7 (2007)(PMID:16959946)
- Hoshino T et al. Pulmonary inflammation and emphysema: role of the cytokines IL-18 and IL-13. Am J Respir Crit Care Med. 176, 49-62 (2007)(PMID:17400729)
- Venkatachalam K et al. Neutralization of interleukin-18 ameliorates ischemia/reperfusion-induced myocardial injury. J Biol Chem. 284,
7853-65 (2009) (PMID:19164288) - Fujiwara H et al. Microbial metabolite sensor GPR43 controls severity of experimental GVHD. Nat Commun. 9, 3674 (2018)(PMID:30201970)
- Yamanishi K et al. Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia. J Transl Med. 16, 314 (2018)(PMID:30453990)
- Chakravarti D et al. Telomere dysfunction activates YAP1 to drive tissue inflammation.Nat Commun. 11, 4766 (2020)
(PMID:32958778)
- Ambati J et al. Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development. Nat Commun. 11, 4737 (2020)(PMID:32968070)
Neutralization - Lertmemongkolchai G et al. Bystander activation of CD8+ T cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens. J. Immunol. 166, 1097-105 (2001)(PMID:11145690)
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