Antibody detailed product information

Code No. CM004-5
Anti-SynCAM (TSLC1/CADM1) mAb-PE
Price ¥63,800
Size 1 mL (50 tests)
Availability (in Japan) 10 or more
（In Japan at 00:05, Apr 19, 2024 in JST）
Clonality Monoclonal
Clone 3E1
Isotype
(Immunized Animal) 		Chicken IgY
Applications FCM　20 µL (Ready for use)  
Immunogen
(Antigen)		 Recombinant SynCAM-Fc fusion protein
Reactivity [Gene ID]

Human[23705]
Storage buffer PBS/1% BSA/0.09% NaN3
Storage temp. 4°C
Conjugate PE
Manufacturer MBL
Alternative names cell adhesion molecule 1, BL2, IGSF4, IGSF4A, NECL2, Necl-2, RA175, ST17, sTSLC-1, sgIGSF
Background SynCAM (Synaptic Cell Adhesion Molecule), also known as TSLC1 (tumor suppressor in lung cancer-1), SgIGSF, or CADM1, is a homophilic, transmembrane Ig-domain containing protein with intracellular PDZ protein-binding motifs. Although originally identified as a tumor suppressor of small lung cell carcinomas, SynCAM appears to be primarily involved in intracellular adhesion and synapse formation. The majority of SynCAM is localized to synaptic sites where it initiates synaptic assembly and synapse differentiation throughout the central nervous system. SynCAM also mediates the cellular adhesion of spermatogenic cells to Sertoli cells and mast cells to fibroblasts.
Related products CM004-3 Anti-SynCAM (TSLC1/CADM1) mAb
CM004-4 Anti-SynCAM (TSLC1/CADM1) mAb-FITC
CM004-6 Anti-SynCAM (TSLC1/CADM1) mAb-Biotin
CM004-A64 Anti-SynCAM (TSLC1/CADM1) mAb-Alexa Fluor™ 647
CM005-3 Anti-SynCAM (TSLC1/CADM1) (Human) mAb
PM084 Normal Chicken IgY
PM084-4 Normal Chicken IgY-FITC
PM084-5 Normal Chicken IgY-PE
Product category Research area:Cancer Neuroscience
Data

Citations

Flow Cytometry

  1. Ishihara Y et al. A Unique T-Cell Receptor Amino Acid Sequence Selected by Human T-Cell Lymphotropic Virus Type 1 Tax301-309-Specific Cytotoxic T Cells in HLA-A24:02-Positive Asymptomatic Carriers and Adult T-Cell Leukemia/Lymphoma Patients. J Virol. 91, e00974-17 (2017)(PMID:28724766)
  2. Sando Y et al. 5-aminolevulinic acid-mediated photodynamic therapy can target aggressive adult T cell leukemia/lymphoma resistant to conventional chemotherapy. Sci Rep. 10, 17237 (2020) (PMID:33057055)
  • The availability is based on the information in Japan at 00:05, Apr 19, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.
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