Antibody detailed product information

Code No.	BMP081
Anti-SLC38A2 (SNAT2) (Human) pAb
Price	¥66,000
Size	100 µL
Availability (in Japan)	1-9 （In Japan at 17:00, Apr 20, 2024 in JST）
Clonality	Polyclonal
Clone	Polyclonal
Isotype (Immunized Animal)	Rabbit Ig (aff.)
Applications	WB　1:500 FCM　1:500 IC　1:500 IH　1:500 (Heat treatment is necessary for paraffin embedded sections.)
Immunogen (Antigen)	Human SLC38A2-derived synthetic peptide
Reactivity [Gene ID]	Human[54407]
Storage buffer	PBS/50% glycerol, pH 7.2
Storage temp.	-20°C
Conjugate	Unlabeled
Manufacturer	MBL
Alternative names	ATA2, SAT2, PRO1068
Background	Members of solute carrier family 38 (SLC38) are sodium-coupled neutral amino acid transporters (SNATs) and resemble transporters involved in the classically described transport system A, which prefer short-chain neutral amino acids like alanine, serine, proline, and glutamine as substrates. SLC38A2, also known as SNAT2, is widely distributed in human tissues and is upregulated under hypertonic conditions and in amino acid deprivation. The depletion of SLC38A2 by siRNA hampers the recovery of cells from hypertonic stress.
Data
Citations	Western Blotting Nardi F et al. Proteasomal modulation of cellular SNAT2 (SLC38A2) abundance and function by unsaturated fatty acid availability. J Biol Chem. 290, 8173-84 (2015)(PMID:25653282) Krokowski D et al. Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity. J Biol Chem. 290, 17822-37 (2015) (PMID:26041779) Hoffmann TM et al. Effects of Sodium and Amino Acid Substrate Availability upon the Expression and Stability of the SNAT2 (SLC38A2) Amino Acid Transporter. Front Pharmacol. 9, 63 (2018) (PMID:29467657)

The availability is based on the information in Japan at 17:00, Apr 20, 2024 in JST.
The special price is shown in red color.
Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.