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HOME > Product search results > Code No. D370-3H Anti-HLA class I (HLA-A,B,C) (Human) mAb

Code No.　D370-3H

Anti-HLA class I (HLA-A,B,C) (Human) mAb

Price

¥35,200

Availability (in Japan)

10 or more

（In Japan at 00:05,
Apr 20, 2024 in JST）

Size

6 mL

This antibody (clone EMR8-5.1) is validated with automated slide stainers.
Data

  • Immunohistochemistry

  • Immunohistochemistry

  • Immunohistochemistry

    HLA class I staining was performed on the Leica Bond RX (Leica Biosystems) using the Bond Polymer Refine Detection Kit (Leica Biosystems; code no. DS980).
Clonality Monoclonal Clone EMR8-5.1
Isotype (Immunized Animal) Mouse IgG1 κ
Applications
IH
Ready for use. (Heat treatment is necessary for paraffin-embedded sections.)  
Immunogen (Antigen) Recombinant HLA-A*24:02 extracellular domain
Reactivity [Gene ID]

Human[3105/3106/3107]
Storage buffer PBS/1% BSA/0.09% NaN3
Storage temp. 4°C Conjugate Unlabeled Manufacturer MBL
Alternative names pan-HLA
Background Human major histocompatibility complex (MHC) class I antigen-epitope peptide complex associated with β2-microglobulin are expressed by all human nucleated cells. It plays an important role in cell-mediated immune responses. Abnormalities in MHC class I antigen surface expression are frequently found in malignancies and infectious diseases. They are often associated with reduced recognition by MHC class I antigen-restricted, tumor or virus-associated antigen-specific cytotoxic T lymphocytes and disease progression. The EMR8-5.1 monoclonal antibody reacts with a non-polymorphic epitope of human MHC class I antigens, HLA-A, -B, and -C. This antibody is suitable for study of MHC class I down-regulation using routine formalin-fixed paraffin-embedded sections by immunohistochemistry.
Related products D367-3 Anti-HLA class I (HLA-A,B,C) (Human) mAb
Product category
Research area
Immunology
Cancer
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  • The availability is based on the information in Japan at 00:05, Apr 20, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications：
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.