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Product search results > Code No. D092-3M2
Anti-CD274 (PD-L1) (Human) mAb (Functional Grade)
Code No. D092-3M2
Anti-CD274 (PD-L1) (Human) mAb (Functional Grade)
Price
¥79,200
Availability (in Japan)
10 or more
（In Japan at 00:05,
Apr 19, 2024 in JST）
Size
100 µL (1 mg/mL)
Data Sheet| Data |
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|---|---|---|---|---|---|
| Clonality | Monoclonal | Clone | MIH3 | ||
| Isotype (Immunized Animal) | Mouse IgG1 | ||||
| Applications |
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| Immunogen (Antigen) | L cells transfected full length human PD-L1 protein | ||||
| Reactivity [Gene ID] | Human[29126] |
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| Storage temp. | -20°C | Conjugate | Unlabeled | Manufacturer | MBL |
| Alternative names | B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1 | ||||
| Background | Programmed death ligand 1 (PD-L1, also known as CD274/B7-H1), a member of B7 family was identified by searching for molecules that share homology with the immunogloblin V and C domains of B7-1 and B7-2 among the human cDNA expressed sequence tags in the National Center for Biotechnology Information database. PD-L1 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA4 subfamily. Although in vitrostudy indicated that the cross-linking of PD-1 by PD-L1 leads to down-regulation of T-cell responses, some studies have shown that T cells stimulated with low levels of anti-CD3 and immobilized PD-L1-Ig were activated, proliferation and production of IFN-g GM-CSF and IL-10 from the T cells were enhanced. The role of PD-L1 is now debatable. | ||||
| Related products | D092-3 Anti-CD274 (PD-L1) (Human) mAb D230-3 Anti-CD274 (PD-L1) (Human) mAb D230-5 Anti-CD274 (PD-L1) (Human) mAb-PE D133-3M2 Anti-CD279 (PD-1) (Human) mAb (Functional Grade) M075-3M2 Mouse IgG1 (isotype control) (Functional Grade) |
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- The availability is based on the information in Japan at 00:05, Apr 19, 2024 in JST.
- The special price is shown in red color.
- Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
- Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization - For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
- For storage temparature: RT: room temparature
- Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.