Anti-ALKBH5 pAb

Price

¥52,800

Availability (in Japan)

1-9

（In Japan at 00:05,
Apr 20, 2024 in JST）

Size

100 µL (1 mg/mL)

Data	Western Blotting Immunoprecipitation
Clonality	Polyclonal	Clone	Polyclonal
Isotype (Immunized Animal)	Rabbit Ig (aff.)
Applications	WB 1:1,000 IP 5 µL/500 µL of cell extract from 5 x 10⁶ cells/sample
Reactivity [Gene ID]	Human[54890], Mouse[268420]
Storage buffer	1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp.	-20°C	Conjugate	Unlabeled	Manufacturer	MBL
Alternative names	ABH5, OFOXD, OFOXD1
Background	N(6)-methyladenosine (m⁶A) is one of the most abundant modified nucleosides found in some viral RNA and eukaryotic RNA including mRNA, tRNA, rRNA and lncRNA. It has been reported that m⁶A modification is involved in the regulation of mRNA export, stability and translation. alkB homolog 5, RNA demethylase (ALKBH5) and FTO are AlkB family proteins that function as mammalian m⁶A demethylases (‘erasers’). ALKBH5 catalyzes the direct removal of m⁶A modification on nuclear RNA and its demethylation affects RNA processing and RNA export. Whereas FTO is highly expressed in brain, ALKBH5 is highly expressed in testis and knockout of Alkbh5 gene in mice exhibits impaired male fertility.
Related products	RN123PW Anti-YTHDF2 pAb RN1001 RIP-Assay Kit
Product category	Research area RNA-RNP Network Brands RiboCluster Profiler™

The availability is based on the information in Japan at 00:05, Apr 20, 2024 in JST.
The special price is shown in red color.
Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
For storage temparature: RT: room temparature
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