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HOME > Product search results > Code No. M220-3 Anti-HB-EGF mAb

Code No. M220-3

Anti-HB-EGF mAb

Price

¥48,000

Availability (in Japan)

10 or more

(In Japan at 01:30,
Nov 23, 2017 in JST)

Size

100 µg/100 µL

Data
  • Western Blotting

  • Immunohistochemistry

Clonality Monoclonal Clone 2-108
Isotype (Immunized Animal) Mouse IgG1 κ
Applications
WB
1 µg/mL  (PMID: 26974561
IP*
reported.  (PMID: 26974561
IC*
reported.  (PMID: 26974561
IH
1 µg/mL  
ELISA*
reported.  (PMID: 26974561
Immunogen (Antigen) extracellular region of HB-EGF
Reactivity [Gene ID]

Human[1839], Mouse(-)(26974561 )

Storage buffer 1 mg/mL in PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names proheparin-binding EGF-like growth factor, Heparin-binding EGF-like growth factor, Diphtheria toxin receptor
Background Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family that bind to and activate the EGF receptor (EGFR/ErbB1) and ErbB4. HB-EGF is synthesized as a single pass membrane-anchored precursor containing a heparin-binding domain, EGF domain, and cytoplasmic domain and then released in the soluble form by ectodomain shedding. HB-EGF is necessary for normal development of the lung, eyelid, and heart and also plays important roles in the development and progression of cancer, such as in cancer metastasis and angiogenesis, and drug-resistance.
Related products D308-3 Anti-HB-EGF (Human) mAb
MI-12-1 Anti-EGF-R (Human) mAb
5346 Ab-Match Human AREG Assembly Kit
Citations

Western Blotting

  1. Iwamoto R et al. Characterization of a Novel Anti-Human HB-EGF Monoclonal Antibody Applicable for Paraffin-Embedded Tissues and Diagnosis of HB-EGF-Related Cancers. Monoclon Anti Immunodiagn Immunother. 35, 73-82 (2016)  Monoclon Antib Immunodiagn Immunother. 35, 73-82 (2016)(PMID:26974561)

Immunoprecipitation

  1. Iwamoto R et al. Characterization of a Novel Anti-Human HB-EGF Monoclonal Antibody Applicable for Paraffin-Embedded Tissues and Diagnosis of HB-EGF-Related Cancers. Monoclon Anti Immunodiagn Immunother. 35, 73-82 (2016)  Monoclon Antib Immunodiagn Immunother. 35, 73-82 (2016)(PMID:26974561)

Immunocytochemistry

  1. Iwamoto R et al. Characterization of a Novel Anti-Human HB-EGF Monoclonal Antibody Applicable for Paraffin-Embedded Tissues and Diagnosis of HB-EGF-Related Cancers. Monoclon Anti Immunodiagn Immunother. 35, 73-82 (2016)  Monoclon Antib Immunodiagn Immunother. 35, 73-82 (2016)(PMID:26974561)

Immunohistochemistry

  1. Iwamoto R et al. Characterization of a Novel Anti-Human HB-EGF Monoclonal Antibody Applicable for Paraffin-Embedded Tissues and Diagnosis of HB-EGF-Related Cancers. Monoclon Anti Immunodiagn Immunother. 35, 73-82 (2016)  Monoclon Antib Immunodiagn Immunother. 35, 73-82 (2016)(PMID:26974561)

ELISA

  1. Iwamoto R et al. Characterization of a Novel Anti-Human HB-EGF Monoclonal Antibody Applicable for Paraffin-Embedded Tissues and Diagnosis of HB-EGF-Related Cancers. Monoclon Anti Immunodiagn Immunother. 35, 73-82 (2016)  Monoclon Antib Immunodiagn Immunother. 35, 73-82 (2016)(PMID:26974561)
Product category
Research area
Cancer
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 01:30, Nov 23, 2017 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.