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HOME > Product search results > Code No. M074-3 Anti-Apaf-1 (Human) mAb

Code No. M074-3

Anti-Apaf-1 (Human) mAb

Price

¥52,800

Availability (in Japan)

10 or more

(In Japan at 17:00,
Apr 19, 2024 in JST)

Size

100 µL (1 mg/mL)

Data
  • Western Blotting

Clonality Monoclonal Clone 5C1
Isotype (Immunized Animal) Mouse IgG1
Applications
WB
5µg/mL  
Immunogen (Antigen) His-tagged human Apaf-1 fusion protein corresponding to N-terminal amino acids (1-421 a. a.)
Reactivity [Gene ID]

Human[317], Mouse(w)[11783], Rat(w)[78963]

Storage buffer 1.0 mg/mL in PBS/50% glycerol
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names apoptotic protease activating factor 1, CED4, APAF-1
References
  1. Pan, G., et al., Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex. J. Biol. Chem. 237, 5841-5845 (1998)(PMID: 9488720
  2. Yoshida, H., et al., Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell 94, 739-750 (1998)(PMID: 9753321
  3. Cecconi, F., et al., Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell 94, 727-737 (1998)(PMID: 9753320
  4. Adrain, C., et al., Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region. J. Biol. Chem. 274, 20855-20860 (1999)(PMID: 10409627
  5. Perkins, C. L., et al., The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis. Cancer Res. 60, 1645-1653 (2000)(PMID: 10749135
Product category
Research area
Apoptosis
この製品に関するお問い合わせをする

  • The availability is based on the information in Japan at 17:00, Apr 19, 2024 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.