Anti-SOD1 (Human) mAb

Western Blotting

1. Hashimoto Y et al. A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta. PNAS 98, 6336-41 (2001)(PMID:11371646)
2. Hashimoto Y et al. The Gtx homeodomain transcription factor exerts neuroprotection using its homeodomain. J. Biol. Chem. 279, 16767-77 (2004)(PMID:14754886)
3. Kanekura K et al. Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants. J Biol Chem. 279, 19247-56 (2004)(PMID:14970233)
4. Schonhoff CM et al. S-nitrosothiol depletion in amyotrophic lateral sclerosis. PNAS 103, 2404-9 (2006)(PMID:16461917)
5. Nawa M et al. A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB. Cell Signal. 20, 493-505 (2008)(PMID:18160256)
6. Doi K et al. Mitochondrial changes in motor neurons of homozygotes of leucine 126 TT deletion SOD1 transgenic mice. Neuropathology 28, 269-76 (2008)(PMID:18179411)
7. Ren G et al. Cu, Zn-superoxide dismutase 1 (SOD1) is a novel target of Puromycin-sensitive aminopeptidase (PSA/NPEPPS): PSA/NPEPPS is a possible modifier of amyotrophic lateral sclerosis. Mol. Neurodegener. 6, 29 (2011)(PMID:21548977)
8. Hineno A et al. Distinctive clinicopathological features of 2 large families with amyotrophic lateral sclerosis having L106V mutation in SOD1 gene. J Neurol Sci. 319, 63-74 (2012)(PMID:22647583)

Immunohistochemistry

1. Morisaki Y et al. Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9. Sci Rep. 6, 27354 (2016)(PMID:27264390)
2. Tokuda E et al. Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis. Mol Neurodegener. 12, 2 (2017)(PMID:28057013)
3. Komine O et al. Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes. Cell Death Differ. (2018) In press.(PMID:29568058)