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HOME > Product search results > Code No. BMP011 Anti-SLC7A5 (LAT1) (Human) pAb

Code No. BMP011

Anti-SLC7A5 (LAT1) (Human) pAb

Price

¥60,000

Availability (in Japan)

10 or more

(In Japan at 00:05,
Sep 20, 2019 in JST)

Size

100 µL

Data
  • Western Blotting

  • Immunohistochemistry

Clonality Polyclonal Clone Polyclonal
Isotype (Immunized Animal) Rabbit Ig (aff.)
Applications
WB
1:1,000  
IH
1:1,000 (Heat treatment is necessary for paraffin embedded sections.)  
Immunogen (Antigen) Human SLC7A5-derived synthetic peptide
Reactivity [Gene ID]

Human[8140]

Storage buffer PBS/50% glycerol, pH 7.2
Storage temp. -20°C Conjugate Unlabeled Manufacturer MBL
Alternative names solute carrier family 7 (amino acid transporter light chain, L system) member 5, E16, CD98, 4F2LC, MPE16
Background SLC7A5, L-type amino acid transporter 1 (LAT1), forms as a heterodimeric complex with the heavy chain of the cell surface antigen 4F2 (4F2hc/CD98). It transports neutral amino acids, most of which are essential amino acids across blood brain barrier. L-dopa, which is commonly used to treat Parkinson’s disease, also enters the brain the LAT1/CD98 complex. In addition, tumors with increased expression of SLC7A5 have been reported. Increased uptake of amino acids through SLC7A5 may facilitate tumor cell growth and survival.
Related products BMP040 Anti-SLC7A3 (CAT3) (Human) pAb
BMP011 Anti-SLC7A5 (LAT1) (Human) pAb
BMP041 Anti-SLC7A8 (LAT2) (Human) pAb
Citations

Western Blotting

  1. Barel M et al. Francisella tularensis regulates the expression of the amino acid transporter SLC1A5 in infected THP-1 human monocytes. Cell Microbiol. 14, 1769-83 (2012)(PMID:22804921)
Product category
Research area
Cancer
Tools
Molecular pathology tools
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  • The availability is based on the information in Japan at 00:05, Sep 20, 2019 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.