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HOME > Product search results > Code No. B-MU540UC Anti-p16 (INK4a) mAb

Code No. B-MU540UC

Anti-p16 (INK4a) mAb

Price

¥68,400

Availability (in Japan)

0
(Contact us)

(In Japan at 00:05,
Aug 25, 2019 in JST)

Size

1 mL

Data
  • Immunohistochemistry

    Cervical carcinoma stained with Anti-p16 using DAB chromogen

Clonality Monoclonal Clone G175-405
Isotype (Immunized Animal) Mouse IgG
Applications
IH
  
Reactivity [Gene ID]

Human

Storage buffer PBS/1% BSA/0.09% NaN3
Storage temp. 4°C Conjugate Unlabeled Manufacturer BIOGENEX LABORATORIES,INC
Background p16/INK4A is a tumor-suppressor protein and that genetic and epigenetic abnormalities in genes controlling the G1 checkpoint can lead to both escape from senescence and cancer formation. The interaction of p16/INK4 family members can be a binary complex with CDK4/6 or ternary complex with cyclin D-bound CDK4/6 and ultimately results in the inhibition of cell cycle progression. As such, expression of p16 INK4A is commonly associated with cellular senescence, and disruption of the p16 INK4A gene is frequently observed in human tumor. The p16/INK4A locus is deleted in a wide spectrum of tumors including melanoma, pancreatic adenocarcinoma, glioblastoma, certain leukemias, non-small cell lung cancer, cervical cancer, and bladder carcinoma.
Product category
Tools
Molecular pathology tools
Brands
BioGenex
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  • The availability is based on the information in Japan at 00:05, Aug 25, 2019 in JST.
  • The special price is shown in red color.
  • Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
  • Abbreviations for applications:
    WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
    FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
    ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
    DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
  • For applications and reactivity:
    *: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
    **: The use is reported from the licenser (Under evaluation or not tested by MBL).
  • For storage temparature: RT: room temparature
  • Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.