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Product search results > Code No. 566-H
Anti-CD117 (c-Kit) (Human) pAb
Code No. 566-H
Anti-CD117 (c-Kit) (Human) pAb
Price
¥32,000
Availability (in Japan)
0
(Contact us)
（In Japan at 00:05,
Apr 19, 2024 in JST）
Size
6 mL
Data Sheet| Data |
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|---|---|---|---|---|---|
| Clonality | Polyclonal | Clone | Polyclonal | ||
| Isotype (Immunized Animal) | Rabbit IgG | ||||
| Applications |
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| Immunogen (Antigen) | Carrier protein conjugated synthetic peptide (C-terminal of c-kit gene product (K963)) | ||||
| Reactivity [Gene ID] | Human[3815] |
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| Storage buffer | 20 mM HEPES/1% BSA/0.135 M NaCl/0.1% NaN3 | ||||
| Storage temp. | 4°C | Conjugate | Unlabeled | Manufacturer | MBL |
| Alternative names | KIT, PBT, SCFR | ||||
| Background | c-Kit, also known as stem cell factor receptor, steel factor receptor or CD117 is classified as a type III receptor tyrosine kinase (RTK) belonging to the platelet-derived growth factor receptor subfamily. Binding of stem cell factor (SCF), known as c-Kit ligand to c-Kit, initiates autophosphorylation of the receptor, subsequently leading to promotes a signal transduction cascade through Ras-Raf-MAP kinase cascade, phosphatidylinositol- 3-kinase, src family kinases, and JAK/STAT pathways. The roles of c-Kit include maturation of hematopoietic and primordial germ cells precursors and melanocytes during embryonic development. In acute myeloid leukemia (AML), c-Kit has been proposed to play a functional role, and becomes target molecule for drug development. | ||||
| Related products | 566 Anti-CD117 (c-Kit) (Human) pAb PM035 Normal Rabbit IgG |
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- The availability is based on the information in Japan at 00:05, Apr 19, 2024 in JST.
- The special price is shown in red color.
- Please note that products cannot be ordered from this website. To purchase the items listed in this website, please contact us or local distributers.
- Abbreviations for applications：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation
FCM: Flow Cytometry, NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization - For applications and reactivity:
*: The use is reported in a research article (Not tested by MBL). Please check the data sheet for detailed information.
**: The use is reported from the licenser (Under evaluation or not tested by MBL).
- For storage temparature: RT: room temparature
- Please note that products in this website might be changed or discontinued without notification in advance for quality improvement.