抗体製品詳細情報

Code No.	D055-3
Anti-M6a (Mouse) mAb
価格(税別)	¥44,000
包装	100 µL (1 mg/mL)
在庫	10以上（2024/04/20 00:05時点）
クローナリティー	Monoclonal
クローン	321
アイソタイプ (免疫動物)	Rat IgG2aκ
使用法	FCM　5-10 µg/mL (final concentration) IH　1-10 µg/mL IF*　reported. （PMID: 18241840 / 28851962） Other(magnetic cell separation)　reported. （PMID: 26702136） Other(Transmission electron microscopy (TEM))　reported. （PMID: 28851962）
免疫原(抗原)	Mouse M6a expressing cells
交差性 [Gene ID]	Mouse[234267]
性状	1 mg/mL in PBS/50% glycerol, pH 7.2
保存温度	-20°C
標識	Unlabeled
メーカー	MBL
別称	Gpm6a
背景	M6 is a membrane glycoprotein that is abundantly expressed on central neurons in the CHS. Two distinct murine M6 cDNA (designated M6a and M6b) whose deduced amino acid sequences are remarkably similar to that of the major CNS myelin protein PLP/DM20 are known. PLP expression is limited to the white matter. M6a appears in post-mitotic neurons of the brain and spinal cord as early as embryonic day 10, and later in the hippocampus, cerebral cortex, and the granule cells of the cerebellum. In contrast, M6b is expressed at early embryonic stage in the ventricular zone of the spinal cord, and later during development in both neurons and glia.
製品カテゴリー	分野:幹細胞研究神経科学エクソソーム
データ
使用文献	Flow Cytometry Lua I et al. Characterization of hepatic stellate cells, portal fibroblasts, and mesothelial cells in normal and fibrotic livers. J Hepatol. 64, 1137-1146 (2016)(PMID:26806818) Immunocytochemistry Aparicio GI et al. Identification of Potential Interacting Proteins With the Extracellular Loops of the Neuronal Glycoprotein M6a by TMT/MS. Front Synaptic Neurosci. 12, 28 (2020)(PMID:32848694) Immunohistochemistry Cooper B et al. Glycoprotein M6a is present in glutamatergic axons in adult rat forebrain and cerebellum. Brain Res. 1197, 1-12 (2008)(PMID:18241840) Zhao J et al. M6a is expressed in the murine neural retina and regulates neurite extension. Mol Vis. 14, 1623-30 (2008)(PMID:18776950) Dorrell C et al. Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers. Mol Cell Endocrinol. 339, 144-50 (2011)(PMID:21539888) Lua I et al. Myofibroblastic Conversion and Regeneration of Mesothelial Cells in Peritoneal and Liver Fibrosis. Am J Pathol. 185, 3258-73 (2015)(PMID:26598235) Li Y et al. Role of TGF-β signaling in differentiation of mesothelial cells to vitamin A-poor hepatic stellate cells in liver fibrosis. Am J Physiol Gastrointest Liver Physiol. 310, G262-72 (2016)(PMID:26702136) Immunofluorescence Cooper B et al. Glycoprotein M6a is present in glutamatergic axons in adult rat forebrain and cerebellum. Brain Res. 1197, 1-12 (2008)(PMID:18241840) Monteleone MC et al. Neural glycoprotein M6a is released in extracellular vesicles and modulated by chronic stressors in blood. Sci Rep. 7, 9788 (2017)(PMID:28851962) Other(magnetic cell separation) Li Y et al. Role of TGF-β signaling in differentiation of mesothelial cells to vitamin A-poor hepatic stellate cells in liver fibrosis. Am J Physiol Gastrointest Liver Physiol. 310, G262-72 (2016)(PMID:26702136) Other(Transmission electron microscopy (TEM)) Monteleone MC et al. Neural glycoprotein M6a is released in extracellular vesicles and modulated by chronic stressors in blood. Sci Rep. 7, 9788 (2017)(PMID:28851962)

※在庫につきましては2024年04月20日 00時05分時点における在庫数を表示してあります。
※価格の赤色表示につきましては、キャンペーン価格の表示となっております。
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※使用法の表記について：
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation,
FCM: Flow Cytometry NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation,
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation,
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
※使用法・交差性の表記について：
*: 論文で報告されております（MBLでは未確認）。詳しくはデータシートをご覧ください。
**: 導入元からの情報です（MBLでは評価中もしくは未確認）。
※保存温度の表記について： RT: 室温
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