トップ > 製品検索結果一覧 > Code No. MEX002-12 Anti-CD63 (LAMP-3) mAb-ALP

Code No. MEX002-12

Anti-CD63 (LAMP-3) mAb-ALP

価格(税別)

¥58,000

在庫

10以上

(2019/09/21 17:00時点)

包装

50 µL

データ
  • ELISA

  • ELISA

クローナリティー Monoclonal クローン C047-1
アイソタイプ
(免疫動物)
Mouse IgG2bκ
使用法
ELISA
1:2,000  
免疫原(抗原) Human prostate carcinoma cell line (PC3) derived exosomes (prepared by ultracentrifugation from cultured supernatant)
交差性
[Gene ID]

Human[967]

性状 50 mM Tris-HCl, 100 mM NaCl, 1% BSA, 0.1% ProClin150 containing stabilizers
保存温度 4°C 標識 AP メーカー MBL
別称 BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN29, TSPAN-29
背景 CD63 antigen, also known as LAMP-3, is a tetraspanin characterized by four transmembrane domains and a member of the transmembrane 4 superfamily. CD63 is the first characterized tetraspanin. CD63 has broad tissue distribution and may play multiple roles in a variety of cellular processes such as immune response and tumorigenesis, but its function has not been elucidated entirely. It is reported that CD63 is abundant in tetraspanin-enriched microdomains (TEMs) and a certain type of cellular compartment, such as late endosomes and lysosomes, while the tetraspanin-rich small lipid bilayers are secreted into extracellular fluid as a certain type of extracellular vesicles, called exosome. Because of various exosome features, CD63, one of the representative exosome surface proteins, is thought to be related to intercellular communication.
関連製品 MEX001-12 Anti-CD9 mAb-ALP
MEX001-3 Anti-CD9 mAb
MEX001-4 Anti-CD9 mAb-FITC
MEX001-6 Anti-CD9 mAb-Biotin
MEX002-3 Anti-CD63 (LAMP-3) mAb
MEX002-4 Anti-CD63 (LAMP-3) mAb-FITC
MEX002-6 Anti-CD63 (LAMP-3) mAb-Biotin
MEX003-3 Anti-CD81 (TAPA1) mAb
MEX003-4 Anti-CD81 (TAPA1) mAb-FITC
MEX003-6 Anti-CD81 (TAPA1) mAb-Biotin
MEX003-12 Anti-CD81 (TAPA1) mAb-ALP
MEX004-6 Anti-CD326 (EpCAM) mAb-Biotin
MEX-E ExoCap™ Nucleic Acid Elution Buffer
D263-3 Anti-CD63 (LAMP-3) (Mouse) mAb
MEX-SA ExoCap™ Streptavidin Kit
参考文献
  1. Mitsunari T et al. Clathrin adaptor AP-2 is essential for early embryonal development. Mol Cell Biol. 25, 9318-23 (2005)(PMID: 16227583
  2. Nishida K et al. Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane. J Cell Biol. 170, 115-26 (2005)(PMID: 15998803
  3. Kabu K et al. Zinc is required for Fc epsilon RI-mediated mast cell activation. J Immunol. 177, 1296-1305 (2006)(PMID: 16818790
  4. Liu Y et al. An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response. J Exp Med. 204, 93-103 (2007)(PMID: 17190838
  5. Simons M, Raposo G. Exosomes--vesicular carriers for intercellular communication. Curr Opin Cell Biol. 21, 575-81 (2009)(PMID: 19442504
  6. Pols MS, Klumperman J. Trafficking and function of the tetraspanin CD63. Exp Cell Res. 315, 1584-92 (2009)(PMID: 18930046
  7. Yoshioka Y et al. Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen. Nat Commun. 5, 3591 (2014)(PMID: 24710016
  8. Melo SA et al. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature 523, 177-82 (2015)(PMID: 26106858
製品
カテゴリー
分野
RNA-RNPネットワーク
がん
細胞膜表面抗原
エクソソーム
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※在庫につきましては2019年09月21日 17時00分時点における在庫数を表示してあります。
※価格の赤色表示につきましては、キャンペーン価格の表示となっております。
※このサイトからは直接注文はできません。ご注意ください。
※使用法の表記について:
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation,
FCM: Flow Cytometry NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation,
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
※使用法・交差性の表記について:
*: 論文で報告されております(MBLでは未確認)。詳しくはデータシートをご覧ください。
**: 導入元からの情報です(MBLでは評価中もしくは未確認)。
※保存温度の表記について: RT: 室温
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