トップ > 製品検索結果一覧 > Code No. M186-3 Anti-LC3 mAb

Code No. M186-3

Anti-LC3 mAb

価格(税別)

¥48,000

在庫

10以上

(2018/09/22 00:05時点)

包装

100 µg/100 µL

データ
  • Western Blotting

クローナリティー Monoclonal クローン 8E10
アイソタイプ
(免疫動物)
Mouse IgG2aκ
使用法
WB
1 µg/mL  
IP*
reported.  (PMID: 28924380
免疫原(抗原) Human LC3, 1-120 aa Recombinant protein
交差性
[Gene ID]

Human[81631], Mouse[67443], Rat[64862], Hamster[100769810]

性状 1 mg/mL in PBS/50% glycerol, pH 7.2
保存温度 -20°C 標識 Unlabeled メーカー MBL
別称 microtubule-associated protein 1 light chain 3 beta, LC3B, ATG8F, MAP1LC3B-a, MAP1A/1BLC3, MAP1LC3B
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M152-3MS Anti-LC3 mAb for My select sampler set
M200-3MS Anti-NRF2 mAb for My select sampler set
8486 Autophagy Watch
M134-3 Anti-Atg4B mAb
M154-3 Anti-Atg12 (Human) mAb
M162-A48 Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor® 488
M162-A59 Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor® 594
M162-A64 Anti-p62 (SQSTM1) (Human) mAb-Alexa Fluor® 647
M186-7 Anti-LC3 mAb-HRP-DirecT
M186-7MS Anti-LC3 mAb-HRP-DirecT for My select sampler set
M200-3 Anti-NRF2 mAb
備考 LC3B に反応します。 LC3A, LC3C, GATE-16, GABARAP には反応しません。
使用文献
使用文献募集中!本製品を使って論文を発表されましたら是非お知らせください。

Western Blotting

  1. Margariti A et al. XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation. J Biol Chem 288, 859-72 (2013)(PMID:23184933)
  2. Mukai R et al. HTLV-1 HBZ positively regulates the mTOR signaling pathway via inhibition of GADD34 activity in the cytoplasm. Oncogene. 33, 2317-28 (2014)(PMID:23708656)
  3. Maejima Y et al. Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nat Med. 19, 1478-88 (2013)(PMID:24141421)
  4. Wang M et al. EGFR-mediated chromatin condensation protects KRAS-mutant cancer cells against ionizing radiation. Cancer Res. 74, 2825-34 (2014)(PMID:24648348)
  5. He R et al. Divergent roles of BECN1 in LC3 lipidation and autophagosomal function. Autophagy 11, 740-7 (2015)(PMID:25955014)
  6. Hasegawa K et al. Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults. Nat Commun. 7, 10943 (2016)(PMID:26971449)
  7. Li Z et al. Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR. PLoS One 11, e0153526 (2016)(PMID:27077655)
  8. Nakanishi T et al. Relationship between triterpenoid anticancer drug resistance, autophagy, and caspase-1 in adult T-cell leukemia. PeerJ 12, e2026 (2016)(PMID:27190722)
  9. Boada-Romero E et al. The T300A Crohn's disease risk polymorphism impairs function of the WD40 domain of ATG16L1. Nat Commun. 7, 11821 (2016)(PMID:27273576)
  10. Sasaki N et al. Chorein interacts with α-tubulin and histone deacetylase 6, and overexpression preserves cell viability during nutrient deprivation in human embryonic kidney 293 cells. FASEB J. 30, 3726-3732 (2016)(PMID:27468757)
  11. Maueröder C et al. Capability of Neutrophils to Form NETs Is Not Directly Influenced by a CMA-Targeting Peptide. Front Immunol. 8, 16 (2017)   (PMID:28191006)
  12. Zhao Z et al. Curcumin accelerates the repair of sciatic nerve injury in rats through reducing Schwann cells apoptosis and promoting myelinization. Front Immunol. 8, 16 (2017)(PMID:28622711)
  13. He R et al. Glucosyltransferase Activity of Clostridium difficile Toxin B Triggers Autophagy-mediated Cell Growth Arrest. Sci Rep. 7, 10532 (2017)(PMID:28874882)
  14. Sun Y et al. Dietary potassium regulates vascular calcification and arterial stiffness. JCI insight 2, e94920 (2017)(PMID:28978809)
  15. Wang H et al. Resveratrol attenuates oxidative damage through activating mitophagy in an in vitro model of Alzheimer's disease. Toxicol Lett. 282, 100-108 (2018)(PMID:29097221)
  16. Wang Y et al. AG-1031 induced autophagic cell death and apoptosis in C6 glioma cells associated with Notch-1 signaling pathway. J Cell Biochem. 119, 5893-5903(2018)(PMID:29575026)
  17. Li YC et al. Opposite Effects of Two Human ATG10 Isoforms on Replication of a HCV Sub-genomic Replicon Are Mediated via Regulating Autophagy Flux in Zebrafish. Front Cell Infect Microbiol. 8, 109 (2018)(PMID:29670865)
  18. Taniguchi K et al. Depletion of gamma-glutamylcyclotransferase in cancer cells induces autophagy followed by cellular senescence. Am J Cancer Res. 8, 650-661 (2018)(PMID:29736310)
  19. Ito Y et al. Synergistic effects of HMG-CoA reductase inhibitor and angiotensin II receptor blocker on load-induced heart failure. FEBS Open Bio. 8, 799-816 (2018)(PMID:29670865)
  20. Shi W et al. Saikosaponin-d inhibits proliferation by up-regulating autophagy via the CaMKKβ-AMPK-mTOR pathway in ADPKD cells. Mol Cell Biochem. (2018) In press. (PMID:29675630)

Immunoprecipitation

  1. Meng XH et al. Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes. Int J Biol Sci. 13, 985-995 (2017)(PMID:28924380)

Immunocytochemistry

  1. Li Z et al. Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR. PLoS One 11, e0153526 (2016)(PMID:27077655)
  2. Meng XH et al. Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes. Int J Biol Sci. 13, 985-995 (2017)(PMID:28924380)
  3. Li W et al. Autophagy is required for human umbilical cord mesenchymal stem cells to improve spatial working memory in APP/PS1 transgenic mouse model. Stem Cell Res Ther. 9, 9 (2018)(PMID:29335016)
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※在庫につきましては2018年09月22日 00時05分時点における在庫数を表示してあります。
※価格の赤色表示につきましては、キャンペーン価格の表示となっております。
※このサイトからは直接注文はできません。ご注意ください。
※使用法の表記について:
WB: Western Blotting, IH: Immunohistochemistry, IC: Immunocytochemistry, IP: Immunoprecipitation,
FCM: Flow Cytometry NT: Neutralization, IF: Immunofluorescence, RIP: RNP Immunoprecipitation,
ChIP: Chromatin Immunoprecipitation, CoIP: Co-Immunoprecipitation
DB: Dot Blotting, NB: Northern Blotting, RNA FISH: RNA Fluorescence in situ hybridization
※使用法・交差性の表記について:
*: 論文で報告されております(MBLでは未確認)。詳しくはデータシートをご覧ください。
**: 導入元からの情報です(MBLでは評価中もしくは未確認)。
※保存温度の表記について: RT: 室温
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